POWERCHINA offre un nouvel exemple de coopération Chine-Côte d’Ivoire au profit du peuple

PÉKIN, 8 décembre 2022 /PRNewswire/ — Un reportage de : CRI Online :

POWERCHINA met en œuvre les concepts de consultation approfondie, de contribution conjointe et de bénéfices partagés, avec tout son cœur et sa sincérité, en Côte d’Ivoire, un pays d’Afrique de l’Ouest éloigné de la mer. La centrale hydroélectrique de Gribo-Popoli construite par POWERCHINA fera du fleuve de Sassandra un nouveau moteur pour le développement socio-économique du pays et de ses voisins.

Ce projet contribuera à atténuer la pénurie d’électricité en Côte d’Ivoire et jouera un rôle positif dans la promotion du développement du Pool énergétique d’Afrique de l’Ouest. Parallèlement, le projet permettra d’économiser de précieuses ressources énergétiques fossiles, de réduire la pollution de l’environnement et d’atténuer la pression environnementale. En outre, il pourra également stimuler efficacement le taux d’emploi, augmenter les recettes fiscales et promouvoir le développement des industries des matériaux et des services de construction. Son exploitation apportera de plus grands avantages sociaux et économiques, jouant un rôle important dans la promotion de l’économie ivoirienne.

Actuellement, différents axes de travail sont en cours de traitement, tels que la construction de l’usine, du déversoir, du barrage, du batardeau, l’excavation de roche et la construction temporaire. Les entreprises de construction ont travaillé ardemment pour surmonter les difficultés technologiques, les conditions géologiques locales complexes, et l’épidémie, reliant les rêves des deux peuples avec la valeur de vivre en harmonie avec les différences.

Kouamo, ingénieur de projet ivoirien, a été encouragé par POWERCHINA, ses avantages à la pointe du secteur et ses riches expériences. Il a exprimé sa profonde gratitude pour la culture d’entreprise et s’est réjoui de la poursuite de la coopération dans les projets de POWERCHINA à l’avenir.

Vaccine R&D Leader Kathrin Jansen and Immunologist Kizzmekia Corbett Awarded Sabin’s Gold Medal and Rising Star Respectively

The Albert B. Sabin Gold Medal and Rising Star Award

The Sabin Vaccine Institute awarded R&D leader Dr. Kathrin Jansen the 2022 Gold Medal for her extraordinary contributions to vaccinology. Immunologist Dr. Kizzmekia Corbett received the 2022 Rising Star award for her work advancing the field of immunization.

WASHINGTON, Dec. 07, 2022 (GLOBE NEWSWIRE) — The Sabin Vaccine Institute today honored two extraordinary scientists for their breakthrough vaccine research that changed the course of the COVID-19 pandemic, advanced public health, and saved countless lives. The 2022 Albert B. Sabin Gold Medal was awarded to vaccine research leader Kathrin U. Jansen, PhD, and the Rising Star to immunologist Kizzmekia Corbett, PhD.

The Gold Medal, now in its 29th year, is Sabin’s highest scientific honor, given annually to a distinguished member of the global health community who has made exceptional contributions to vaccinology or a complementary field. Past award recipients include leaders of vaccinology and vaccine advocacy such as Drs. Barney Graham, Carol Baker, Anne Gershon, Bill Foege, and Myron Levine.

Dr. Jansen was selected for her nearly three decades of commitment to advancing vaccine research and development (R&D) for a range of challenging diseases from COVID-19 to HPV and pneumonia, all of which afflict adults and children in low-and middle-income countries with already fragile health care systems.

This past August, Dr. Jansen retired as the senior vice president and head of vaccine research and development at Pfizer Inc. There, Dr. Jansen led global vaccines R&D with responsibilities ranging from discovery to post-marketing commitments. In collaboration with BioNTech, Dr. Jansen spearheaded the development of a COVID-19 vaccine that would become the first FDA and WHO-authorized COVID-19 vaccine and is the first-ever approved vaccine to use an mRNA platform.

Dr. Jansen’s leadership at Pfizer also produced newer versions of a widely used pneumococcal conjugate vaccine and vaccine candidates to prevent Streptococcus pneumoniae, respiratory syncytial virus (RSV), meningococcal infections, and Group B streptococcus. Previously, she directed vaccine R&D efforts at Merck Research Laboratories and led the development of the world’s first cervical cancer vaccine. She also contributed to programs for rotavirus, mumps, measles and rubella.

“We are delighted to recognize Dr. Jansen with our Gold Medal award for her commitment to furthering vaccines and tackling tough scientific challenges in the interest of benefitting humanity and saving lives,” says Amy Finan, Sabin’s chief executive officer. “Throughout her career, she has demonstrated a unique passion for answering perplexing research questions and making bold decisions that led to impactful public health milestones.”

Dr. Jansen said she was “humbled” by the honor. “When you look at all the previous Gold Medal recipients, they are colleagues and friends that you know and have interacted and worked with for years – passionate people, all dedicated to making a healthier world.”

Sabin’s Rising Star Dr. Corbett is an assistant professor of immunology and infectious diseases at Harvard T.H. Chan School of Public Health. A viral immunologist by training, Dr. Corbett works to advance vaccine development for pandemic preparedness and to build public confidence in vaccines, particularly among communities of color facing health disparities. While at the National Institutes of Health she was a member of the team whose research on the novel coronavirus laid the groundwork for the COVID-19 Moderna vaccine – the first candidate to be tested in Phase 1 clinical trials in the U.S.

Dr. Corbett’s research has also included a universal influenza vaccine, dengue, and respiratory syncytial virus. Currently, she leads a laboratory focused on novel coronaviruses and other infectious diseases that aims to inform vaccine development against potential future pandemics. She is also a leading advocate for STEM education, health care equity, and community-based public health outreach.

“Sabin is delighted to name Dr. Corbett this year’s Rising Star,” says Finan. “Her contributions to vaccine development are matched only by her dedication to shoring up vaccine confidence, especially among skeptics. She has done incredible work explaining the scientific rigor behind vaccines and is inspiring the next generation of researchers and public health heroes.”

“It’s a really big honor for me to win this award,” says Dr. Corbett. “Having just started my career and my own lab, winning this Rising Star Award suggests that – number one – I have a long way to go but – number two – that I am capable, which is especially good to hear from my peers, mentors and other more experienced scientists.”

About the Sabin Vaccine Institute

The Sabin Vaccine Institute is a leading advocate for expanding vaccine access and uptake globally, advancing vaccine research and development, and amplifying vaccine knowledge and innovation. Unlocking the potential of vaccines through partnership, Sabin has built a robust ecosystem of funders, innovators, implementers, practitioners, policy makers and public stakeholders to advance its vision of a future free from preventable diseases. As a non-profit with more than two decades of experience, Sabin is committed to finding solutions that last and extending the full benefits of vaccines to all people, regardless of who they are or where they live. At Sabin, we believe in the power of vaccines to change the world.

For more information, visit https://www.sabin.org/ and follow us on Twitter @sabinvaccine.

Media contact: Rajee Suri, rajee.suri@sabin.org

A photo accompanying this announcement is available at: https://www.globenewswire.com/NewsRoom/AttachmentNg/66127064-3ffb-4f40-9010-7d9da33b625b

GlobeNewswire Distribution ID 8708580

Kathrin Jansen, Líder de Pesquisa e Desenvolvimento de Vacinas, e Kizzmekia Corbett, Imunologista, Premiadas com as Medalhas Gold e Rising Star da Sabin, respectivamente

WASHINGTON, Dec. 07, 2022 (GLOBE NEWSWIRE) — O Sabin Vaccine Institute homenageou hoje duas cientistas extraordinárias pelas suas pesquisas inovadoras sobre vacinas que mudaram o curso da pandemia da COVID-19, avançaram a saúde pública e salvaram inúmeras vidas. A Gold Medal Albert B. Sabin de 2022 foi concedida à líder de pesquisa de vacinas Kathrin U. Jansen, PhD, e a Rising Star à imunologista Kizzmekia Corbett, PhD.

A Gold Medal, agora no seu 29º ano, é a maior honra científica da Sabin, concedida anualmente a um membro distinto da comunidade de saúde global pelas suas contribuições excepcionais para o campo de vacinação ou complementar. Os vencedores dos prêmios anteriores incluem líderes de vacinação e defesa de vacinas como os Drs. Barney Graham, Carol Baker, Anne Gershon, Bill Foege e Myron Levine.

A Dra. Jansen foi selecionada por suas quase três décadas de compromisso com o avanço da pesquisa e desenvolvimento de vacinas (P&D) para uma série de doenças desafiadoras, desde COVID-19 até HPV e pneumonia, que afetam adultos e crianças de países de baixa e média renda com sistemas de saúde já frágeis.

Em agosto passado, a Dra. Jansen se aposentou como vice-presidente sênior e chefe de pesquisa e desenvolvimento de vacinas da Pfizer Inc, onde liderou a pesquisa e desenvolvimento de vacinas globais com responsabilidades que vão desde a descoberta até os compromissos pós-comercialização. Em colaboração com a BioNTech, a Dra. Jansen liderou o desenvolvimento da primeira vacina em uma plataforma de mRNA contra a COVID-19 a ser autorizada pela FDA e pela OMS.

A liderança da Dra. Jansen na Pfizer também resultou em versões mais recentes de uma vacina pneumocócica conjugada amplamente usada e candidatos a vacina para prevenir o Streptococcus pneumoniae, vírus sincicial respiratório (VSR), infecções meningocócicas, e o estreptococo do Grupo B. Anteriormente, ela dirigiu os esforços de pesquisa e desenvolvimento de vacinas na Merck Research Laboratories e liderou o desenvolvimento da primeira vacina contra o câncer de colo do útero do mundo. Ela também contribuiu para programas de rotavírus, caxumba, sarampo e rubéola.

“Estamos muito contentes em conceder à Dra. Jansen o nosso prêmio Gold Medal por sua dedicação à promoção das vacinas e ao enfrentamento de desafios científicos visando beneficiar a humanidade e salvar vidas”, disse Amy Finan, diretora executiva da Sabin. “Ao longo da sua carreira, ela demonstrou um entusiasmo único por responder a perguntas de pesquisa desconcertantes e tomar decisões ousadas que levaram a marcos impactantes para a saúde pública.”

A Dra. Jansen disse que se sentiu “honrada” com a premiação. “Os ganhadores anteriores da Gold Medal são colegas e amigos com os quais eu interagi e trabalho com eles há anos – pessoas entusiasmadas, dedicadas a tornar o mundo mais saudável para todos.”

A Dra. Corbett, recebedora do prêmio Rising Star da Sabin, é professora assistente de imunologia e doenças infecciosas da Harvard T.H. Chan School of Public Health. Imunologista viral, a Dra. Corbett trabalha para promover o desenvolvimento de vacinas em antecipação às pandemias e para aumentar a confiança do público nas vacinas, particularmente entre comunidades de pessoas de cor que enfrentam disparidades de saúde. No National Institutes of Health ela foi membro da equipe cuja pesquisa sobre o novo coronavírus lançou as bases para a vacina COVID-19 Moderna – a primeira candidata a ser testada em ensaios clínicos de Fase 1 nos EUA.

A pesquisa da Dra. Corbett também incluiu uma vacina universal contra a gripe, dengue e vírus sincicial respiratório. Atualmente ela lidera um laboratório focado nos novos coronavírus e outras doenças infecciosas, visando informar o desenvolvimento de vacinas contra possíveis pandemias futuras. Ela também é uma das principais defensoras da educação STEM, da equidade nos cuidados de saúde, e do alcance da saúde pública nas comunidades.

“A Sabin tem o prazer de premiar a Dra. Corbett com o Rising Star deste ano”, disse Finan. “Sua contribuição para o desenvolvimento da vacina acompanha sua dedicação em aumentar a confiança nas vacinas, especialmente entre os céticos. Ela fez um trabalho incrível explicando o rigor científico por trás das vacinas, inspirando a próxima geração de pesquisadores e heróis da saúde pública.”

“É uma grande honra para mim ganhar este prêmio”, disse a Dra. Corbett. “O recebimento deste Prêmio Rising Star no início da minha carreira no meu próprio laboratório sugere que – primeiro – tenho um longo caminho a percorrer, mas – segundo– que sou capaz. E isso é especialmente bom de ouvir dos meus colegas, mentores e outros cientistas mais experientes.”

Sobre o Sabin Vaccine Institute

O Sabin Vaccine Institute é um dos principais defensores da expansão do acesso e uso de vacinas em todo o mundo, do avanço da pesquisa e desenvolvimento de vacinas e da ampliação do conhecimento e inovação das vacinas. Revelando o potencial das vacinas através da parceria, o Sabin criou um ecossistema robusto de financiadores, inovadores, implementadores, profissionais, formuladores de políticas e partes interessadas públicas para avançar sua visão de um futuro livre de doenças evitáveis. Como uma organização sem fins lucrativos com mais de duas décadas de experiência, o Sabin está empenhado em encontrar soluções duradouras que levem todos os benefícios das vacinas a todas as pessoas, independentemente de quem sejam ou de onde vivem. No Sabin, acreditamos no poder das vacinas para mudar o mundo.

Para mais informação, visite https://www.sabin.org/ e siga-nos no Twitter @SabinVaccine.

Contato com a Mídia: Rajee Suri, rajee.suri@sabin.org

Foto deste comunicado disponível em: https://www.globenewswire.com/NewsRoom/AttachmentNg/66127064-3ffb-4f40-9010-7d9da33b625b

GlobeNewswire Distribution ID 8709489

La leader en recherche et développement de vaccins Kathrin Jansen et l’immunologue Kizzmekia Corbett se voient remettre respectivement la Médaille d’or et le prix Rising Star de Sabin

WASHINGTON, 07 déc. 2022 (GLOBE NEWSWIRE) — Le Sabin Vaccine Institute a récompensé aujourd’hui deux scientifiques extraordinaires pour leurs recherches de pointe en matière de vaccins qui ont permis de changer le cours de la pandémie de COVID-19, de faire progresser la santé publique et de sauver d’innombrables vies. La Médaille d’or Albert B. Sabin 2022 a été décernée à la leader de la recherche en vaccins Kathrin U. Jansen, PhD, tandis que le prix Rising Star (étoile montante) a été attribué à l’immunologue Kizzmekia Corbett, PhD.

La Médaille d’or, qui en est à sa 29e édition, est le plus prestigieux honneur scientifique de Sabin, décerné chaque année à un membre distingué de la communauté mondiale de la santé qui a apporté des contributions exceptionnelles à la vaccinologie ou à un domaine complémentaire. Les anciens lauréats incluent des chefs de file dans les domaines de la vaccinologie et de la sensibilisation aux vaccins tels que les Drs Barney Graham, Carol Baker, Anne Gershon, Bill Foege et Myron Levine.

La Dr Jansen a été sélectionnée pour ses près de 30 ans d’engagement à faire avancer la recherche et le développement (R&D) en matière de vaccins pour diverses maladies difficiles à traiter, de la COVID-19 au HPV en passant par la pneumonie, toutes susceptibles de toucher les adultes comme les enfants dans les pays à revenus faibles et modérés aux systèmes de santé déjà fragiles.

Au mois d’août passé, la Dr Jansen a quitté ses fonctions de vice-présidente sénior et de responsable de la recherche et du développement de vaccins chez Pfizer Inc. Dans cette entreprise, la Dr Jansen a mené une R&D en matière de vaccins à l’échelle mondiale, ses responsabilités allant de la découverte aux engagements post-marketing. En collaboration avec BioNTech, la Dr Jansen a été le fer de lance du développement d’un vaccin contre la COVID-19 qui est devenu le premier autorisé par la FDA et l’OMS, mais également le tout premier vaccin approuvé à utiliser une plateforme ARNm.

Le leadership de la Dr Jansen chez Pfizer a également permis de produire de nouvelles versions d’un vaccin et de candidats vaccins conjugués antipneumocoques largement utilisés dans le but de prévenir le pneumocoque, le virus respiratoire syncytial (VRS), les infections méningocoques et le streptocoque B. Elle dirigeait auparavant les initiatives de R&D en matière de vaccins chez Merck Research Laboratories et a conduit le développement du tout premier vaccin contre le cancer cervical au monde. Elle a aussi contribué à des programmes de lutte contre les rotavirus, les oreillons, la rougeole et la rubéole.

« Nous sommes ravis d’offrir la Médaille d’or à la Dr Jansen pour reconnaître son engagement à améliorer les vaccins et sa lutte face à des défis scientifiques difficiles, tout cela pour le bien de l’humanité et pour sauver des vies », a déclaré Amy Finan, présidente-directrice générale de Sabin. « Tout au long de sa carrière, elle a fait montre d’une passion exceptionnelle pour répondre aux questions de recherche les plus complexes et a pris des décisions audacieuses qui ont permis d’atteindre des étapes majeures révolutionnant la santé publique. »

La Dr Jansen a déclaré être « honorée » de recevoir ce prix. « Quand je regarde tous les précédents lauréats de la Médaille d’or, je ne vois que des collègues et amis avec qui j’ai parlé et travaillé pendant des années : des gens passionnés, voulant tous œuvrer pour un monde en meilleure santé. »

La Dr Corbett, qui a remporté le prix Rising Star de Sabin, est professeure-adjointe en immunologie et maladies contagieuses à la Harvard T.H. Chan School of Public Health. Immunologue virale de formation, la Dr Corbett œuvre dans le but de faire avancer le développement de vaccins pour préparer le monde aux pandémies et pour favoriser la confiance du public à l’égard des vaccins, particulièrement dans les communautés de couleur confrontées à des disparités en matière de santé. Quand elle travaillait aux National Institutes of Health, elle était membre de l’équipe dont les recherches sur le nouveau coronavirus ont posé les bases du vaccin Moderna contre la COVID-19, le premier candidat à avoir été testé dans des essais cliniques de phase 1 aux États-Unis.

Les recherches de la Dr Corbett s’intéressaient aussi à un vaccin universel contre la grippe, la dengue et le virus respiratoire syncytial. Elle dirige actuellement un laboratoire axé sur les nouveaux coronavirus et autres maladies contagieuses dans le but d’informer le développement de vaccins face à de futures pandémies potentielles. Elle défend aussi ardemment les études STIM, l’égalité dans les soins de santé et la sensibilisation communautaire sur la santé publique.

« Sabin se réjouit de nommer la Dr Corbett pour le prix Rising Star de cette année », a déclaré Mme Finan. « Ses contributions au développement de vaccins n’ont d’égal que son dévouement à stimuler la confiance à l’égard de ceux-ci, en particulier parmi les sceptiques. Elle a réalisé un travail incroyable pour expliquer la rigueur scientifique qui se cache derrière la conception de vaccins et inspire la nouvelle génération de chercheurs et de héros de la santé publique. »

« C’est un très grand honneur pour moi de remporter ce prix », a déclaré la Dr Corbett. « Comme je viens seulement de débuter ma carrière et de lancer mon propre laboratoire, remporter ce prix Rising Star suggère que, premièrement, j’ai encore un long chemin à parcourir mais que, deuxièmement, j’en suis capable, ce qui est particulièrement agréable à entendre de la part de mes pairs, mentors et d’autres scientifiques plus expérimentés. »

À propos du Sabin Vaccine Institute

Le Sabin Vaccine Institute est l’un des principaux défenseurs de l’élargissement de l’accès aux vaccins et de leur adoption à l’échelle mondiale, de l’avancement de la recherche et du développement de vaccins et de l’amplification des connaissances et de l’innovation en matière de vaccins. Libérant le potentiel des vaccins par le partenariat, Sabin a bâtit un écosystème robuste de bailleurs de fonds, innovateurs, agents de mise en œuvre, praticiens, décideurs politiques et parties prenantes publiques pour faire avancer sa vision d’un avenir où les maladies évitables ont enfin disparu. En tant qu’organisation sans but lucratif comptant plus de deux décennies d’expérience, Sabin s’est engagée à trouver des solutions qui durent et à étendre tous les bienfaits des vaccins à l’ensemble des individus, peu importe qui ils sont et où ils résident. Chez Sabin, nous sommes convaincus que les vaccins ont le pouvoir de changer le monde.

Pour de plus amples informations, rendez-vous sur le site https://www.sabin.org/ et suivez-nous sur Twitter @sabinvaccine.

Contact auprès des médias : Rajee Suri, rajee.suri@sabin.org

Une photo accompagnant ce communiqué de presse est disponible à l’adresse : https://www.globenewswire.com/NewsRoom/AttachmentNg/66127064-3ffb-4f40-9010-7d9da33b625b

GlobeNewswire Distribution ID 8709489

UNHCR Darfur Operation Sitrep (October 2022)

4.2 M Persons of Concern

188,203 refugees and asylum seekers1

3M IDPs

940,154 IDP returnees

152,020 Sudanese who have spontaneously returned from Chad from 2018 to date (verification is ongoing)

45,977 households (Approximately 230,000 individuals) affected by heavy rains since the beginning of the rainy season in July 2022.

5105 households (refugees, IDPs and host community) affected from floods received NFI kits.

Key Highlights

Insecurity incidents reported across Darfur include robbery with violence targeting humanitarian organizations, carjackings, tensions between armed groups, killings, and gender-based violence (GBV). The continuing high number of incidents can be attributed to the current economic situation, increased commodity prices and occasional clashes between herders and farmers linked to the agricultural season.

Health Situation in Darfur is seriously affected by various epidemics, mainly Dengue Hemorrhagic Fever, an increase in malaria cases, and Hepatitis E. Although the State Ministry of Health and partners are implementing response activities, a shortage of funds remains a significant challenge to cover all affected areas. In addition, there is a severe shortage of anti-malaria medication, especially at health centres in refugee locations. In response to the high number of malaria cases, UNHCR has included mosquito nets in NFI kits during ongoing distribution for flood-affected and vulnerable families.

IDPs from Sortoni Gathering Site in North Darfur were displaced to Jabal Marrah, Central Darfur due to tensions between armed groups. An estimated 1,700 households are in dire need of food, healthcare, and shelter. However, the situation in the area remains volatile, and lack of access has prevented humanitarian organizations from conducting needs assessment and response activities.

Refugee Protection

Joint refugee verification and biometric registration exercise by Commission of Refugees and UNHCR are ongoing in Al Lait, North Darfur. Follow-up registration and verification exercises will continue in East and South Darfur. The exercise started early in the year in Central Darfur, where refugees from Chad and the Central African Republic (CAR) reside. Registration is an important protection tool, ensuring refugees access their fundamental rights, humanitarian assistance & prevents statelessness.

Education Assessment has commenced in refugee-hosting states in Darfur to gather accurate data on refugee education. The education sector is significantly underfunded. The exercise will help better understand existing gaps and challenges facing refugee children to access quality education. UNHCR and partners completed the exercise in Al Lait Locality, North Darfur, where 150 respondents were interviewed, including refugee students, headteachers, teachers and members of the Parents Teachers Association (PTA). Findings of the assessment will be shared upon completion of the exercise in all States.

Education activities: 656 refugee children in Nyala town, South Darfur, received school uniforms and educational materials. Approximately 60% of the target refugee children received school uniforms and educational materials in the State. In addition, UNHCR led a successful back-to-school campaign in Al Lait settlements in North Darfur which saw the enrolment of 1,746 1st graders.

Source: UN High Commissioner for Refugees

WHO: COVID-19 Sets Back Global Malaria Efforts, Especially in Africa

The COVID-19 pandemic has set global malaria control efforts back, especially in Africa, the World Health Organization says.

However, this year’s World Malaria Report says countries were able to lessen disruptions to prevention, testing and treatment.

In 2019, before the pandemic struck, there were 568,000 malaria deaths. Despite the pandemic and other humanitarian emergencies, WHO information shows concerted action by countries has prevented the worst potential impacts of COVID-19-related disruptions to malaria services.

WHO officials say the world has largely managed to salvage many of the gains made against malaria during the past 20 years.

Abdisalan Noor, head of the WHO Global Malaria Program’s Strategic Information unit, said malaria cases dramatically increased in the first year of the pandemic. However, he said the number of cases last year remained largely the same as in 2020.

“Overall, however, the pandemic and its related disruptions have led to increases in malaria burden over the last two years, and we estimate that about 63,000 deaths and about 13 million cases [were] attributed to disruptions during the COVID-19 pandemic,” he said.

Most deaths and cases have occurred in the WHO African region, Noor said, adding that progress in malaria control is continuing. For example, he said 11 countries with the world’s highest malaria levels have largely held the line against the disease during the pandemic. Among them are Burkina Faso, the Democratic Republic of Congo, India, Mali and Tanzania,

Despite the challenges posed by the pandemic, Noor said nearly 300 million insecticide-treated bed nets were distributed to susceptible families. Bed nets are regarded as the most important tool against malaria, and their declining effectiveness is of concern.

Noor cited growing insecticide resistance and households’ decreasing retention of bed nets as major problems.

“In particular, because of the physical durability of the bed net itself as well as the maintenance of the bed net in the household … we are not getting the gains we would have hoped for from the ITN [insecticide-treated net], which essentially means that given that mass campaigns have been every three years, we have a considerable period between campaigns when people are not receiving effective protection,” he said.

WHO officials consider the current setback as a temporary glitch on the road to global malaria elimination. They say key opportunities, such as a new generation of malaria control tools, could help accelerate progress toward this goal.

They say long-lasting bed nets with new insecticide combinations and other innovations in vector control are in the offing, and by late next year, the world’s first malaria vaccine will be offered to millions of children. Also, they add, other lifesaving malaria vaccines are in development.

Source: Voice of America

Despite continued impact of COVID-19, malaria cases and deaths remained stable in 2021

Geneva, New data released today by the World Health Organization (WHO) show that countries around the world largely held the line against further setbacks to malaria prevention, testing and treatment services in 2021.

According to this year’s World malaria report, there were an estimated 619 000 malaria deaths globally in 2021 compared to 625 000 in the first year of the pandemic. In 2019, before the pandemic struck, the number of deaths stood at 568 000.

Malaria cases continued to rise between 2020 and 2021, but at a slower rate than in the period 2019 to 2020. The global tally of malaria cases reached 247 million in 2021, compared to 245 million in 2020 and 232 million in 2019.

“Following a marked increase in malaria cases and deaths in the first year of the COVID-19 pandemic, malaria-affected countries redoubled their efforts and were able to mitigate the worst impacts of Covid-related disruptions to malaria services,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “We face many challenges, but there are many reasons for hope. By strengthening the response, understanding and mitigating the risks, building resilience and accelerating research, there is every reason to dream of a malaria-free future.”

Strong national-level commitment key to success

Insecticide treated bednets (ITNs) are the primary vector control tool used in most malaria-endemic countries and, in 2020, countries distributed more ITNs than in any year on record. In 2021, ITN distributions were strong overall and at similar levels to pre-pandemic years: 171 million ITNs planned for distribution, 128 million (75%) were distributed.

However, eight countries (Benin, Eritrea, Indonesia, Nigeria, Solomon Islands, Thailand, Uganda and Vanuatu) distributed less than 60% of their ITNs, and seven countries (Botswana, Central African Republic, Chad, Haiti, India, Pakistan and Sierra Leone) did not distribute any ITNs.

Seasonal malaria chemoprevention (SMC) is recommended to prevent the disease among children living in areas with highly seasonal malaria transmission in Africa. In 2021, further expansion of this intervention reached nearly 45 million children per SMC cycle in 15 African countries, a major increase from 33.4 million in 2020 and 22.1 million in 2019.

At the same time, most countries succeeded in maintaining malaria testing and treatment during the pandemic. Despite supply chain and logistical challenges during the pandemic, malaria-endemic countries distributed a record number of rapid diagnostic tests (RDTs) to health facilities in 2020. In 2021, countries distributed 223 million RDTs, a similar level reported before the pandemic.

Artemisinin-based combination therapies (ACTs) are the most effective treatment for P. falciparum malaria. Malaria-endemic countries delivered an estimated 242 million ACTs worldwide in 2021 compared to 239 million ACTs in 2019.

A convergence of threats undermining efforts

Despite successes, our efforts face many challenges, particularly in the African Region, which shouldered about 95% of cases and 96% of deaths globally in 2021.

Disruptions during the pandemic and converging humanitarian crises, health system challenges, restricted funding, rising biological threats and a decline in the effectiveness of core disease-cutting tools threaten the global response to malaria.

“Despite progress, the African region continues to be hardest hit by this deadly disease,” said Dr Matshidiso Moeti, WHO Regional Director for Africa. “New tools—and the funding to deploy these—are urgently needed to help us defeat malaria.”

Total funding for malaria in 2021 was US$ 3.5 billion, an increase from the two previous years but well below the estimated US$ 7.3 billion required globally to stay on track to defeat malaria.

At the same time, a decline in the effectiveness of core malaria control tools, most crucially ITNs, is impeding further progress against malaria. Threats to this key prevention tool include insecticide resistance; insufficient access; loss of ITNs due to the stresses of day-to-day use outpacing replacement; and changing behaviour of mosquitoes, which appear to be biting early before people go to bed, and resting outdoors, thereby evading exposure to insecticides.

Other risks are also rising, including parasite mutations affecting the performance of rapid diagnostic tests; growing parasite resistance to the drugs used to treat malaria; and the invasion in Africa of an urban-adapted mosquito that is resistant to many of the insecticides used today.

Key opportunities to accelerate progress

WHO recently launched 2 strategies to support countries in the African continent as they work to build a more resilient response to malaria: a strategy to curb antimalarial drug resistance and an initiative to stop the spread of the Anopheles stephensi malaria vector. Additionally, a new global framework to respond to malaria in urban areas, developed jointly by WHO and UN-Habitat, provides guidance for city leaders and malaria stakeholders.

Meanwhile, a robust research and development pipeline is set to bring a new generation of malaria control tools that could help accelerate progress towards global targets.

Key opportunities include long-lasting bednets with new insecticide combinations and other innovations in vector control, including targeted baits that attract mosquitoes, spatial repellents and genetic engineering of mosquitoes. New diagnostic tests are also under development, as are next-generation life-saving medicines to respond to antimalarial drug resistance.

From late 2023 onwards, millions of children living in areas of highest risk of illness and death from malaria are also expected to benefit from the life-saving impact of the world’s first malaria vaccine, RTS,S. Other malaria vaccines are in the product development pipeline.

According to the report, these opportunities cannot be fully exploited without intensified efforts to ensure that nobody is left behind. Malaria-endemic countries should continue to strengthen their health systems, using a primary health care approach, to ensure access to quality services and interventions for all in need.

Source: World Health Organization